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Nursing Complex Health Alterations I
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Overview

Prepares learners to care for patients with cardiovascular, respiratory, endocrine, hematologic, fluid/electrolyte, acid-base, and comfort alterations

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Estimated Dates
Digital Textbook: March 2027
Print Textbook: June 2027
Audiobook: June 2027
Next Edition: 2030
Annual Student Impact

1,669 students | 0 high school students | $383,269 student savings

Complex Health Alterations I is a comprehensive textbook designed to prepare nursing students and healthcare learners to care for patients experiencing complex health challenges across the lifespan. This resource focuses on providing and evaluating nursing care for patients with alterations in the cardiovascular, respiratory, endocrine, and hematologic systems. It also addresses the management of fluid and electrolyte imbalances, acid-base disturbances, and issues related to patient comfort. With clear explanations, evidence-based practices, and real-world scenarios, this textbook equips learners with the knowledge and critical thinking skills needed to deliver safe, effective, and compassionate care to individuals facing complex health conditions.

Course Competency 1: Integrate nursing care for clients with coronary artery disease

  • Define cardiac output and factors affecting cardiac output.
  • Identify focused assessments for altered cardiac output.
  • Define preload, contractility, and afterload and how they can be affected by collaborative interventions.
  • Identify normal lab values for cholesterol, LDL, HDL, BUN, EGFR and creatinine and relate how they can be affected by CAD.
  • Describe how preload, contractility, and afterload can be altered.
  • Outline how to perform emergency care procedures (CPR, Respiratory support, AED).
  • Outline nursing responsibilities for patients undergoing hemodynamic monitoring.
  • Identify what determines and/or affects systolic and diastolic blood pressure.
  • Explain what mean arterial pressure (MAP) reflects.
  • Outline the procedural steps for accurate manual measurement of blood pressure.
  • Describe the classification of hypertension.
  • Explain the long-term effects of hypertension on the heart, blood vessels and target organs.
  • Explain how each of the following affects blood pressure: diuretics, ACE inhibitors, alpha agonist/antagonists, beta-adrenergic blockers, IV Nitroprusside, calcium channel blockers, high sodium diet, stress, catecholamine release, aldosterone, ADH, ANP.
  • Explain how or why orthostatic hypotension occurs.
  • Suggest measures for preventing problems associated with orthostatic hypotension.
  • Explain risk factors, assessment findings and collaborative treatment required for hypertensive crisis.
  • Outline priority health promotion teaching topics for patients with hypertension.
  • Relate classes of medications to care for a patient with coronary artery disease or MI: antilipemics, antiplatelets, ACE inhibitors, ARBs, beta blockers, calcium channel blockers, nitroglycerin (short acting, long acting and IV), morphine and heparin.
  • Prioritize care for a patient with chest pain.
  • Differentiate symptoms of chronic angina from those indicating acute coronary syndrome.
  • Differentiate the nurse’s role in the care of patients experiencing a STEMI versus a non-STEMI.
  • Explain how MIs are diagnosed and the significance of standard lab and ECG findings.
  • Contrast ECG results indicating ischemia, injury and infarction.
  • Identify nursing responsibilities for a patient following coronary artery bypass surgery, including monitoring for potential complications.
  • Describe cardiac rehabilitation and its benefits.
  • Identify pre- and post-procedural nursing responsibilities while caring for patients undergoing an exercise stress test, cardiac angiogram, cardiac angioplasty (PCI).
  • Outline priority teaching topics for a patient with CAD, MI or post-CABG.
  • Identify reversible causes of dysrhythmias (5 H's and 5 T's).
  • Identify common dysrhythmias on ECG results and relate collaborative interventions for each (sinus bradycardia, sinus tachycardia, atrial fibrillation, premature ventricular tachycardia, ventricular tachycardia, ventricular fibrillation, asystole).
  • Contrast synchronized cardioversion (with or without conscious sedation) and defibrillation.
  • Identify when PVCs are considered dangerous.
  • Explain common protocols initiated by nurses to maintain a patient's cardiovascular status (chest pain, STEMI, electrolyte replacement).
  • Describe the nurse's role in a code.
  • Differentiate when pacemakers or ICDs are needed.
  • Identify the learning needs of patients with pacemakers and ICDs.
  • Outline the New York Heart Association Classification of heart failure and how it can be used to plan nursing care for patients with heart failure.
  • Differentiate manifestations of diastolic versus systolic heart failure, and manifestations of left- versus right-sided heart failure.
  • Explain how the body attempts to compensate in CHF and how these mechanisms eventually result in decompensation.
  • Differentiate between manifestations of stable left-sided heart failure versus acute pulmonary edema.
  • Explain how lung disease promotes the development of cor pulmonale.
  • Describe the nurse's role in a code.
  • Contrast the signs and symptoms of stable heart failure with those occurring during an acute exacerbation.
  • Outline collaborative interventions for an acute exacerbation of heart failure including common medications, BiPAP, intra-aortic balloon pump (IABP) and ventricular assist devices (VAD).

Course Competency 2: Integrate nursing care for clients with alterations in cardiovascular system

  • Describe the development of atherosclerotic plaque and how atherosclerosis is related to modifiable risk factors.
  • Contrast signs, symptoms, and interventions associated with chronic PAD, acute arterial occlusion, venous insufficiency and deep vein thrombosis.
  • Differentiate manifestations of arterial and venous ulcers and collaborative interventions for each.
  • Explain collateral circulation and its effects following arterial obstruction.
  • Explain the risk factors, prevention and treatment of varicose veins.
  • Contrast manifestations and collaborative interventions for an arterial aneurysm versus dissection.
  • Contrast manifestations and collaborative care for valvular regurgitation versus stenosis.
  • Explain how infectious endocarditis can lead to valvular dysfunction.
  • Differentiate among risk factors, manifestations and collaborative care for infective endocarditis, pericarditis and cardiomyopathy.
  • Explain how pericardial effusion and cardiac tamponade can be caused by pericarditis and the manifestations and collaborative care required.
  • Explain why cardiac tamponade is a life-threatening situation.
  • Relate the pathophysiology of rheumatic carditis to its manifestations and collaborative care.
  • Outline symptoms of rejection of a heart transplant.
  • Differentiate cyanotic and acyanotic congenital heart defects.
  • Outline nursing responsibilities for infants and children with congenital heart defects.
  • Explore the process of organ transplantation and associated ethical implications.
  • Outline the shunts in fetal circulation (ductus venosus, foramen ovale and ductus arteriosus) and how blood flow changes when the baby is born.
  • Outline priority teaching topics for parents with children with congenital heart defects.

Course Competency 3: Integrate nursing care for clients with acute alterations in the respiratory system

  • Describe surfactant and how it affects ventilation.
  • Identify factors that will decrease the diffusion of gasses across the alveolar-capillary membrane.
  • Describe the manifestations of hypoxia, hypercapnia and acidosis.
  • Explain why caution is required when administering high levels of oxygen to people with chronic hypoxia.
  • Review nursing’s role in oxygen administration and other respiratory cares.
  • Review nursing responsibilities for patients receiving respiratory assistance (oxygen therapy, CPAP, BiPAP, PEEP, mechanical ventilation).
  • Review the collaborative role of respiratory therapists when caring for patients with respiratory disorders.
  • Explain how ABGs are used in the diagnosis and collaborative care of patients with acute respiratory disorders.
  • Outline nursing responsibilities associated with procedures such as thoracentesis and bronchoscopy.
  • Outline health promotion teaching about smoking cessation.
  • Describe the symptoms associated with acute respiratory distress.
  • Explain risk factors, signs and symptoms of ARDS.
  • Explain why patients with respiratory distress may eventually become apneic.
  • Explain ventilator settings such as FiO2, Tidal volume, and PEEP.
  • Describe potential complications of PEEP and how to assess if they are occurring.
  • Outline potential complications for patients on a ventilator and how they can be prevented.
  • Compare/contrast causes and interventions for low pressure and high pressure alarms for a patient on a ventilator.
  • Describe the effects of inflammation on the airways and pulmonary tissues.
  • Outline infection control measures for patients with respiratory infections.
  • Explain when respiratory infections are a public health concern.
  • Explain how to interpret a Mantoux/ppd test.
  • Describe how active tuberculosis is diagnosed.
  • Describe specific isolation precautions for a patient with an active TB infection.
  • Explain why multiple antibiotics are used for an extended period of time for patients with active tuberculosis.
  • Describe who is at risk for atelectasis and how it can be prevented.
  • Explain how atelectasis can lead to pneumonia.
  • Outline patient instructions for proper use of incentive spirometry according to current guidelines.
  • Differentiate between Community Acquired Pneumonia, Hospital Acquired Pneumonia and Ventilator Associated Pneumonia.
  • Explain how symptoms of pneumonia are often different in an elderly patient.
  • Outline risk factors and interventions to prevent pulmonary emboli.
  • Explain why pulmonary emboli are a perfusion, not a ventilation, respiratory problem.
  • Explain why cardiac output may be decreased in a patient with pulmonary emboli.
  • Describe nursing responsibilities associated with the treatment of pulmonary edema using IV furosemide.
  • Contrast the signs, symptoms and collaborative care of patients with pulmonary edema versus pleural effusion.
  • Differentiate nursing responsibilities when caring for patients with pneumothorax, hemothorax and tension pneumothorax.
  • Explain why a tension pneumothorax is life-threatening and requires emergent care.
  • Describe nursing responsibilities associated with caring for patients with chest tube drainage systems.
  • Relate the Tdap vaccine to the recent emergence of pertussis in children and adults.
  • Describe the symptoms of pertussis and current guidelines for the treatment of patients and their close household contacts.
  • Outline infection control and public health measures for a patient with pertussis.
  • Differentiate between home management of croup and when hospital care is required.
  • Outline acute collaborative care for a patient with croup.
  • Relate the pathophysiology of epiglottitis to symptoms and collaborative care.
  • Explain why epiglottitis is potentially a life-threatening condition.
  • Outline infection control measures for a patient with bronchiolitis.

Course Competency 4: Integrate nursing care for clients with chronic alterations in the respiratory system

  • Explain how lung disorders can cause cor pulmonale.
  • Relate spirometry terms such as FVC, FEV1 and residual volume to the collaborative treatment of asthma and COPD.
  • Explain the therapeutic effects of the flutter device (acapella).
  • Outline nursing interventions to address the anxiety that commonly occurs in patients with dyspnea.
  • Describe the pathophysiology, potential complications, and collaborative interventions for sleep apnea.
  • Explain how each of the following can result in a restrictive/interstitial lung disorder: dusts, drugs, radiation, fibrosis, connective tissue diseases.
  • Describe the post-operative needs of patients following laryngectomy and pneumonectomy.
  • Outline the risk factors for lung cancer and common collaborative treatments.
  • Outline nursing responsibilities when caring for a patient with a tracheostomy, including trach care, suctioning, and promoting communication.
  • Explain the purpose of cuff inflation and its potential adverse effects.
  • Outline how to prevent aspiration in a patient with a tracheostomy.
  • Describe assessments and interventions for tube obstruction.
  • Explain the function of fenestrated tubes and caps/valves.
  • Outline the weaning procedure for a patient with a tracheostomy.
  • Outline priority teaching topics for home management for a patient with a tracheostomy.
  • Outline steps to perform if the tracheostomy tube becomes dislodged.
  • Describe how the three major problems associated with asthma (bronchoconstriction, mucosal edema, mucus production) affect oxygenation and the work of breathing.
  • Describe how the collaborative care of patients with asthma is based on the step classification.
  • Explain how "personal best" peak flow readings and the Asthma Action Plan are used for optimal self management of asthma.
  • Differentiate from "control" medications versus "quick relief" medications for asthma and associated patient education.
  • Describe common ABG results for a patient in an early asthma attack and how the results change as the patient's respiratory status worsens.
  • Outline manifestations and collaborative care for a patient in status asthmaticus.
  • Differentiate between manifestations of chronic stable COPD versus those signifying an acute exacerbation of COPD.
  • Explain why people with COPD may develop a barrel chest (increase AP diameter).
  • Explain the role of alpha-1-antitrypsin in the development of emphysema.
  • Explain why people with COPD may develop secondary polycythemia.
  • Explain why BiPAP therapy is often more beneficial than just oxygen therapy for a patient with an acute exacerbation of COPD.
  • Relate the pathophysiology of COPD to common classes of medications used to treat it.
  • Explain why weight loss is often associated with COPD and common nutritional interventions.
  • Explain why pursed lip breathing is an effective breathing technique for patients with COPD.
  • Describe collaborative care for patients with "end stage COPD."
  • Explain why cystic fibrosis can cause both respiratory and digestive problems.
  • Outline collaborative care for patients with cystic fibrosis.
  • Explain common causes of early death for patients with cystic fibrosis and how they can be prevented.

Course Competency 5: Integrate nursing care for clients with alterations in hematology

  • Explain the process of hematopoiesis (RBCs, WBCs, and platelets).
  • Describe how oxygen and carbon dioxide are transported through the bloodstream.
  • Explain the relationship between hematological problems, the need for oxygen, and common symptoms.
  • Describe the role of platelets and clotting factors in hemostasis.
  • Briefly outline the coagulation pathways.
  • Identify abnormal values for the following lab tests: hemoglobin, hematocrit, white blood cell count, plateletncount, INR, aPTT.
  • Explain the effects of anticoagulants, fibrinolytics and inhibitors of platelet activity on hematologic function.
  •  Explain how to modify the environment to protect patients with neutropenia and thrombocytopenia.
  • Identify priority concerns for a patient undergoing bone marrow biopsy.
  • Relate the common symptoms of anemia to the level of hemoglobin.
  • Explain how severe anemia can lead to chest pain and heart failure.
  • Predict how renal failure can result in anemia.
  • Explain when iron, vitamin B12 injections, and protein are needed to treat anemia.
  • Relate the development of jaundice to hemolytic anemias.
  • Review nursing concerns when transfusing blood and blood products.
  • Identify the causes and treatment for polycythemia.
  • Describe neutropenic precautions/protective environment and when they are indicated.
  • Differentiate between leukemias and malignant lymphomas.
  • Relate the manifestations of multiple myeloma to pathophysiology.
  • Identify conditions/disorders/situations that increase the risk of clot formation.
  • Explain when and how blood clots are dissolved.
  • Explain therapeutic effects of daily aspirin and pre-operative or pre-procedural concerns related to aspirin.
  • Identify appropriate nursing responses to abnormal lab results related to bleeding and clotting (e.g. high or low INR, aPTT, platelet, D-dimer).
  • Identify nursing concerns when a patient is diagnosed with heparin-induced thrombocytopenia and other forms of thrombocytopenia.

Course Competency 6: Integrate nursing care for clients with alterations in the endocrine system

  • Outline the major features of the stress response.
  • Explain the major effects of each of the following substances released during the stress response: ADH, Aldosterone, epinephrine, norepinephrine, and cortisol.
  • Identify expected assessment findings in acute and chronic stress.
  • Explain how stress alters nutritional requirements.
  • Explain nursing responsibilities in assessing a patient's coping status and suggesting coping strategies and resources.
  • Describe how to evaluate if patients' coping strategies are effective.
  • Apply the nursing process to common endocrine disorders such as Diabetes Mellitus, Cushing's Syndrome, Adrenal insufficiency, SIADH, Diabetes Insipidus, Hyperthyroidism and Hypothyroidism.
  • Identify the relationship of TSH, T3 and T4 levels and thyroid dysfunction.
  • Explain how and when endocrine disorders can become life-threatening.
  • Discuss the pathophysiology of cell starvation, hyperglycemia, and dehydration in diabetes mellitus.
  • Differentiate between Type I and Type II diabetes mellitus.
  • Identify etiological factors associated with Type I and Type II diabetes.
  • Relate factors that influence blood glucose levels.
  • Contrast Somogyi effect and Dawn phenomenon.
  • Identify abnormal values for the following lab tests: fasting blood glucose, hemoglobin A1C.
  • Describe oral agents and types of insulin used to treat diabetes.
  • Identify the effects of insulin on serum potassium level.
  • Identify aspects nurses should consider when administering anti-diabetic agents.
  • Describe “carb counting” based insulin regimens.
  • Describe proper foot care for a patient with diabetes.
  • Develop a plan for teaching patients self-management (including diet, travel, sick day care).
  • Explain how the effectiveness of diabetes treatment can be monitored.
  • Explain why healing is impaired in patients with diabetes.
  • Predict possible acute and chronic complications of diabetes mellitus.
  • Prioritize nursing interventions for patients with DKA and HHS.
  • Discuss developmental concerns in caring for patients with diabetes.
  • Identify other providers’ importance in collaborative management of diabetes.

Course Competency 7: Integrate nursing care for clients with alterations in fluid and electrolyte balance

  • Explain how fluid volume and electrolytes are regulated.
  • Explain the development and treatment of edema.
  • Identify factors that can increase the risk of fluid and electrolyte imbalances.
  • Explain how sodium and water imbalances affect neurological functioning.
  • Explain the effects of altered potassium levels on membrane potential and the implications for the nurse.
  • Identify abnormal values for the following lab tests: sodium, potassium.
  • Differentiate between osmosis, diffusion, filtration, and active transport.
  • Explain why severe fluid and/or electrolyte imbalances can become life-threatening.

Course Competency 8: Integrate nursing care for clients with alterations in acid-base balance

  • Explain where acids and bases come from in the body.
  • Predict patients at risk for acid base imbalance.
  • Explain the roles of the lungs, kidneys, and chemical buffers in maintaining acid base balance.
  • Identify signs and symptoms of acidosis and alkalosis.
  • Interpret basic arterial blood gas laboratory results.
  • Predict the signs and symptoms observed with compensation for various acid-base imbalances.
  • Suggest treatment measures for various acid-base imbalances.

Course Competency 9: Integrate nursing care for clients with pain and alterations in comfort

  • Differentiate various types of pain including: acute, chronic, referred, and neuropathic.
  • Explain the decision-making process for selecting the appropriate medication to treat various types of pain (consider algorithms such as the WHO ladder).
  • Identify nursing strategies for managing the side effects of pain medications.
  • Discuss the care of a patient receiving patient-controlled analgesia.
  • Explain how non-pharmacologic, complementary, and alternative treatments for pain and nausea can be incorporated into the plan of care.
  • Suggest ways in which a nurse can help meet the needs of the families of patients with acute or chronic pain.
  • Incorporate standards of practice for pain management into a plan of care for patients with acute pain, chronic pain, and end of life pain.
  • Identify patients who might benefit from palliative care.
  • Outline goals of palliative care.
  • Discuss ways in which the nurse can promote comfort during the dying process.

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